Achieving Low parts-per Quadrillion (ppq) Detection Limits for PFAS Analysis in Drinking Water

Separation Science, in collaboration with
SCIEX, offers an on-demand presentation introducing new ways to reduce contamination and modify sample preparation by elevating the sensitivity of mass spectrometers to reach low, single digit ppq (pg/L) detection levels for PFAS analysis in drinking water.

Format: On-demand

Duration: Approximately 1 hour


Andrew_Patterson_80Andrew Patterson
Technical Director, Eurofins Specialty Services
Andrew brings 20 years of experience in the environmental industry with a focus on HRGS/HRMS analyses and LC-MS/MS analysis of PFAS. Before Eurofins, Andrew was the Technical Director for Vista Analytical Laboratory in Northern California where he developed all aspects of PFAS capability within the lab. Before Vista, Andrew worked in both the HRMS and LCMS laboratories at Alta Analytical, with a focus on developing fringe EPA methods (1614, 1699, 1694). Andrew holds a Bachelor of Science in Microbiology/Biochemistry from Cal Poly San Luis Obispo.

Craig_Butt_80Craig Butt
Applications Lead - PFAS, SCIEX
Craig is currently the applications lead for all things PFAS at SCIEX. He has contributed to a variety of PFAS-specific applications, including EPA methods 537.1 and 533. In his 20 years of mass spectrometry experience, Craig has published 48 peer-reviewed manuscripts. Craig obtained his PhD in environmental chemistry at the University of Toronto, investigating the fate of PFAS in biological systems. He was then a post-doc at NSERC and Duke, before joining SCIEX and continuing to collaborate with industry experts.



SCIEX Logo 2019





Event Overview

In June 2022, the US EPA announced new drinking water advisory levels (HALs) for 4 per- and polyfluoroalkyl substances (PFAS). In particular, perfluorooctanoic acid (PFOA) required a detection limit of 4 parts-per-quadrillion (ppq).

The scientific community were collectively shaken.
These trace-level ppq levels for PFOA and PFOS in the 2022 EPA drinking water HALs demand an unprecedented level of cleanliness and instrument sensitivity – which ultimately necessitates newer, robust analytical techniques. SCIEX and Eurofins partnered up to discover new ways to reduce contamination, modify sample preparation, and elevate the sensitivity of mass spectrometers to reach low, single digit ppq (pg/L) detection levels.

By viewing this presentation you will learn:

  • how SCIEX and Eurofins became the first to market achieving 4 ppq detection levels
  • about the advantages of a positive-pressure, HEPA-filtered clean room
  • why a modified SPE method requiring only a 25x concentration step eliminated the need for sample blow down and reconstitution
  • how the SCIEX 7500 system was able to detect single digit pg/L levels
  • how can we minimize contamination for challenging methods.

Plus by registering you will also be able to access the following resources...

  • PFAS Analysis
    Trace-level detection and quantification of PFAS.
  • Technical note
    Achieving low parts-per-quadrillion detection limits for PFAS analysis in drinking water.
  • PFAS eBook
    In-depth PFAS resources from experts in the field, with content you cannot afford to be without.
  • The pursuit: A lifetime of exposure
    Chris Higgins and Craig Butt revisit the history and the surprising behaviour of PFAS in the environment.
  • PFAS fireside chats with Dr. Craig Butt
    Tune in to hear thought leaders in the field sharing their ideas and knowledge.
  • PFAS resources
    Find the latest resources from Phenomenex for PFAS analysis.

To register for this on-demand webinar please complete the form on the right. 

Registrants to this webinar are covered by the Eclipse Business Media Privacy Policy. Information you provide will be shared with the sponsors for this content. Eclipse Business Media Ltd may contact you to offer you content based on your specific interests. You may opt-out at any time.