Demystifying comprehensive two-dimensional

gas chromatography (GC×GC)

By watching this presentation you will:

  • Learn the basics of GC×GC and what it offers over and above standard GC
  • Debunk the myths of GC×GC being a ‘research-only’ tool
  • See how cutting-edge software tools can simplify everyday use of GC×GC
  • Familiarise yourself with the latest GC×GC applications

Event overview

In this presentation SepSolve Analytical demonstrates how the latest advances in GC×GC hardware and software are extending the capabilities of the technique from the niche to the mainstream. Flow modulation of the gas stream overcomes the practical difficulties of applying GC×GC for routine analyses and has reduced cost of ownership. Easy-to-use chemometrics tools make life easier by preventing data processing becoming the bottleneck of analytical workflows.

We cover some fascinating examples of real-life applications that have benefited from the separating power of GC×GC, in both research and routine laboratories. These include biomarker discovery, aroma profiling and environmental monitoring:

  • Total petroleum hydrocarbons (TPH) – Robust and routine monitoring of total petroleum hydrocarbons (TPH) in environmental matrices using GC×GC-FID.

  • Chemical fingerprinting of pyrolysis oils – Detailed characterisation of pyrolysis oils from solid waste plastics using GC×GC–TOF MS to identify possible contaminants, and help to refine process design.

  • Biomarker discovery – Thermal desorption coupled with GC×GC–TOF MS to capture comprehensive breath profiles and uncover potential biomarkers of disease.

  • Aroma profiling – Comparison of whisky aroma profiles by SPME–GC×GC–TOF MS to distinguish between whiskies from different regions and evaluate the impact of maturation.

What you need to know:

Format: On-demand

Duration: Approximately 60 minutes

Who should watch it:

  • GC and GC-MS users who want to enhance their ability to analyse complex samples
  • Separation scientists who want to find out more about GC×GC
  • GC×GC practitioners wanting to further their knowledge on recent advances in applications, hardware and software


LauraMcGregor_200Laura McGregor
Product Marketing Manager, SepSolve Analytical
Laura McGregor received an M.Chem. in chemistry from the University of St Andrews, UK, followed by an M.Sc. in forensic science at the University of Strathclyde, UK. Her Ph.D. in environmental forensics, also at the University of Strathclyde, sparked her interest in GC×GC and she has been a strong advocate of the technique ever since. In her current role as Product Marketing Manager at SepSolve Analytical, she continues to apply GC×GC–TOF MS to challenging applications.





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