The quantification of PFAS from environmental samples is a complicated undertaking due to the high levels of contamination typically observed in most laboratories. Sample preparation and extraction are critical aspects of any workflow for PFAS analysis and demands a serious level of attention, like the LCMS operation. In this talk, Dr. Bradley Clarke from the Unversity of Melbourne, Australia, provides an overview of the sample extraction processes for the extraction of PFAS from water, soil, and serum, including steps taken to reduce sample volume without sacrificing limits of quantification.

By watching this presentation you will learn about:

  • Common techniques used for water analysis using solid-phase extraction (SPE).
  • Approaches for minimising sample volume and use of costly internal standards.
  • Workflows for the quick extraction of PFAS from solid matrices.


BradClarke_200Dr. Bradley Clarke (Senior Lecturer in Environmental Science and Analytical Chemistry, University of Melbourne, Australia)
Dr Brad Clarke is currently a Senior Lecturer at the University of Melbourne (Australia) the chief investigator from the Australian Laboratory for Emerging Contaminants (ALEC). ALEC is a dedicated partnership between private industry and equipped with state-of-the-art analytical instrumentation (LCTQ, GCTQ, LCQTOF, GCQTOF) to solve issues of emerging contaminants. Brad’s research focusses on assessing the risk to public health and the environment from persistent organic pollutants (POPs) with a particularly focus on legacy and emerging per and polyfluoroalkyl substances (PFAS), novel flame retardants and microplastics. Prior to joining the University of Melbourne, Brad was the Program manager for the Environmental Science degree at RMIT University and has held postdoctoral positions at Imperial College London and the University of Arizona.

In addition, you'll be able to watch the following on-demand presentations...

AddPres_ChenLatest Regulations & Standards on PFAS Testing in the Materials Industry
Dr Yuhong Chen (Global Materials Segment, Applied Markets, Agilent Technologies)

AddPres_GilSampling and Analysis of Volatile PFAS in Air by TD-GC-MS
Carlos Gil (Business Development Manager, Markes International GmbH)

AddPres_BaumannStreamlined PFAS Annotation and Visualization with FluoroMatch Flow and Visualizer
Stephen Baumann (Application Applied Segment Manager, Agilent Technologies)

AddPres_ThaxtonUsing Thermal Desorption and GC-MS/MS for the Analysis of PFAS Compounds in Air for Improved Detectability & Reliability
Kurt Thaxton (Gerstel)

As well as download the following educational assets...

PFAS2022_Resource1Your Guide to Targeted Quantification & Screening of PFAS Compounds in Environmental Matrices

AgilentPFAS_Resource2Get your lab up to speed for PFAS analysis with the Agilent start-to-finish drinking and surface water eMethod

AgilentPFAS2022_Resource3Customer Testimonial: Watch How Sanexen Environmental Services Meets Client Needs for PFAS Testing

AgilentPFAS2022_Resource4Get Ahead and Stay Ahead with Comprehensive Workflows for Extraction, Screening, Quantification, and Reporting of PFAS in Water Samples

AgilentPFAS2022_Resource5Meet the Challenges of PFAS Soil Testing in an Evolving Regulatory Framework With Start-to-Finish Workflows

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